CD3e Golden Syrian Hamster anti-Mouse, Clone: eBio500A2 (500A2), Functional Grade, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0033-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15238347

Quantity Price
1 £ 72.77 / 100µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Gene Alias CD3 epsilon
Formulation aqueous buffer, no sodium azide
Species Reactivity Mouse
Format Purified
Clone eBio500A2 (500A2)
Host Species Golden Syrian Hamster
Isotype IgG
Monoclonal or Polyclonal Monoclonal
Antigen CD3e
Quantity 100μg
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Primary or Secondary Primary

The eBio500A2 monoclonal antibody reacts with the 25 kD epsilon subunit of the mouse CD3 complex. CD3 subunits γ, δ and ε are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells, as well as NKT cells. Binding of eBio500A2 to CD3 initiates the intracellular biochemical pathway resulting in cellular activation and proliferation. The 500A2 antibody is able to partially cross-block the 17A2 and 145-2C11 antibodies, indicating that all three of these anti-CD3 antibodies recognize distinct but overlapping epitopes.