CD3e Golden Syrian Hamster anti-Mouse, Alexa Fluor 700, Clone: 500A2, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 56-0033-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15312100

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
Add to basket


Description and Specification

Specification

Format Conjugated
Isotype IgG
Antigen CD3e
Clone eBio500A2 (500A2)
Gene Alias CD3 epsilon
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Conjugate Alexa Fluor 700
Primary or Secondary Primary
Concentration 0.2mg/mL
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Quantity 25μg
Host Species Golden Syrian Hamster
Applications Flow Cytometry

The eBio500A2 monoclonal antibody reacts with the 25 kD epsilon subunit of the mouse CD3 complex. CD3 subunits γ, δ and ε are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells, as well as NKT cells. Binding of eBio500A2 to CD3 initiates the intracellular biochemical pathway resulting in cellular activation and proliferation. The 500A2 antibody is able to partially cross-block the 17A2 and 145-2C11 antibodies, indicating that all three of these anti-CD3 antibodies recognize distinct but overlapping epitopes.