CD3e Armenian Hamster anti-Mouse, eFluor 450, Clone: 145-2C11, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0031-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15371670

Quantity Price
1 £ 142.93 / 100µg
EU Stock 12
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Description and Specification

Specification

Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Concentration 0.2mg/mL
Antigen CD3e
Quantity 100μg
Clone 145-2C11
Isotype IgG
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Gene Alias CD3 epsilon
Regulatory Status RUO
Format Conjugated
Species Reactivity Mouse
Conjugate eFluor 450
Host Species Armenian Hamster
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.