CD3e Armenian Hamster anti-Mouse, APC-eFluor 780, Clone: 145-2C11, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 47-0031-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15381410

Quantity Price
1 £ 54.42 / 25µg
EU Stock 1
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Description and Specification

Specification

Gene Alias CD3 epsilon
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Concentration 0.2mg/mL
Conjugate APC-eFluor 780
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Antigen CD3e
Format Conjugated
Applications Flow Cytometry
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Species Reactivity Mouse
Clone 145-2C11
Host Species Armenian Hamster
Isotype IgG
Quantity 25μg

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.