CD371 (Clec12A) Mouse anti-Human, PE, Clone: HB3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9878-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15507266

Quantity Price
1 £ 66.65 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone HB3
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD371 (Clec12A)
Host Species Mouse
Concentration 5μL (0.125μg)/test
Applications Flow Cytometry
Isotype IgG1
Quantity 25 tests
Species Reactivity Human
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Conjugate PE
Gene Alias Myeloid Inhibitory C-type Lectin-like Receptor

This HB3 monoclonal antibody reacts with human CD371, which is also known as Clec12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL). CD371 is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2. CD371 is expressed mainly on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression of CD371 on NK cells remains controversial. Although the function of CD371 is not fully understood, studies suggest that this receptor plays a role in inflammation and LPS activation.