CD371 (Clec12A) Mouse anti-Human, PE, Clone: HB3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9878-41

25TEST Anti-Human CD371 (Clec12A) PE

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15507266

Quantity Price
1 £ 101.6 / 25 tests
Estimated Shipment date
from Supplier 21-02-2017
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Clone HB3
Antigen CD371 (Clec12A)
Format Conjugated
Gene Alias Myeloid Inhibitory C-type Lectin-like Receptor
Host Species Mouse
Applications Flow Cytometry
Isotype IgG1
Quantity 25 tests
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Concentration 5μL (0.125μg)/test
Conjugate PE

This HB3 monoclonal antibody reacts with human CD371, which is also known as Clec12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL). CD371 is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2. CD371 is expressed mainly on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression of CD371 on NK cells remains controversial. Although the function of CD371 is not fully understood, studies suggest that this receptor plays a role in inflammation and LPS activation.