CD365 (Tim-1) Monoclonal Antibody (RMT1-4), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5861-95

Product Code. 17108505

Description

The RMT1-4 MAb reacts with mouse CD365 (also known as TIM1 and HAVCR1) and is a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. CD365 has been found on activated CD4+ T cells, mast cells, and a subset of B cells. CD365 is involved in renal injury, tissue homeostasis, and T cell costimulation. CD365 promotes the differentiation of Th2 cells and the production of IL-4. CD365 can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself. CD365 and TIM4 can mediate uptake of apoptotic cells through recognition of phosphatidylserine. CD365, as well as the other TIM family members, are associated with susceptibility to atopic and autoimmune diseases. In humans, certain polymorphic variants of CD365 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV).

CD365 (Tim-1) Monoclonal antibody specifically detects CD365 (Tim-1) in Mouse samples. It is validated for Flow Cytometry

Specifications

• Antigen: CD365 (Tim-1)
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: Q5QNS5
• Host Species: Rat
• Quantity: 10 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: RMT1-4
• Conjugate: Unconjugated
• Gene: Havcr1
• Gene Alias: AI503787; CD365; HAVCR; Havcr1; HAVCR-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171283
• Content And Storage: 4° C
• Form: Liquid