CD36 Mouse, anti-Human, Unconjugated, Clone: FA6-152, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60084

Product Code. 15940282

Description

• The FA6-152 antibody reacts with CD36, an ∼88 kDa transmembrane glycoprotein that functions as a scavenger receptor, cell adhesion molecule, and signal transducer on the surface of many types of cells including platelets, monocytes, macrophages, erythrocyte precursors, endothelial and epithelial cells, and some macrophage-derived dendritic cells
• The topology of the protein is thought to comprise a large extracellular loop with the N- and C-termini both inserted through the cell membrane
• CD36 binds multiple ligands such as thrombospondin, collagen, lipoproteins, and long-chain fatty acids, and has evident roles in the phagocytic clearance of apoptotic cells, inhibition of angiogenesis, metabolism of glucose and fatty acids, inflammation, and the pathogenesis of malaria
• The epitope for FA6-152 reportedly resides within an immunodominant domain of CD36 comprising amino acids 155 - 183

Specifications

• Antigen: CD36
• Classification: Monoclonal
• Conjugate: Unconjugated
• Quantity: 100 μg
• Target Species: Human, Rat
• Cell Type: Monocytes, Other

• Applications: Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: FA6-152
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG1 κ