Invitrogen™ CD357 (AITR/GITR) Monoclonal Antibody (eBioAITR), APC-eFluor™ 780, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ 47-5875-42

Product Code. 16340904

Description

Mouse Monoclonal Antibody

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Specifications

• Antigen: CD357 (AITR/GITR)
• Classification: Monoclonal
• Concentration: 5 μL/Test
• Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
• Gene Accession No.: Q9Y5U5
• Gene Symbols: Tnfrsf18
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8784
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: eBioAITR
• Conjugate: APC-eFluor 780
• Gene: Tnfrsf18
• Gene Alias: Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364
• Host Species: Mouse
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ