CD34 Mouse, anti-Human, PE, Clone: 563, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60119PE

Product Code. 17179141

Description

• CD34 is an ∼105 - 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines
• The frequency of CD34+ cells is low in bone marrow (1 - 4%), cord blood (∼1%), and peripheral blood (< 0.1%)
• CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation
• Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage
• The 563 antibody recognizes a class III epitope (resistant to neuraminidase and O-glycoprotease)
• Clone 563 also cross-reacts with CD34+ cells of rhesus, cynomolgus, and pigtailed macaques, but not baboons

Specifications

• Antigen: CD34
• Classification: Monoclonal
• Conjugate: PE
• Quantity: 50 Tests
• Target Species: Cynomolgus, Human, Rhesus Monkey
• Cell Type: Hematopoietic Stem and Progenitor Cells

• Applications: Flow Cytometry
• Clone: 563
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG1 κ