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CD34 Mouse anti-Human, eFluor 450, Clone: 4H11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-0349-41

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15539666

  • £67.24 / 25 tests


Estimated Shipment date
from Supplier 29-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The 4H11 monoclonal antibody reacts with human CD34, also known as mucosialin. CD34 belongs to a protein family which also includes endoglycan and podocalyxin. Members of this family are single pass transmembrane proteins with a heavily glycosylated extracellular and N-terminal mucin domain. CD34 was first identified as an antigen expressed on hematopoietic progenitors, and has since been extensively used as a marker to isolate cells capable of hematopoietic cell engraftment. In spite of this, the function of CD34 remains unresolved. In addition to expression on hematopoietic progenitors, CD34 is expressed on some populations of mesenchymal stem cells, tumor cell lines, and by vascular endothelia in the adult. Epitopes of CD34 have been assigned to three classes (class I, II or III) based on their differential sensitivity to enzymatic cleavage by neuraminidase, chymopapain, or O-glycoprotease. According to this analysis, the 4H11 antibody belongs to class III, indicating that it reacts with a protein epitope.
Description & Specifications

Specifications

CD34
4H11
eFluor 450
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (1μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Mucosialin, Class III epitope
IgG1
RUO
Primary
Human