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CD34 Antibody (ICO-115), Novus Biologicals™

Product Code. 18418531 Shop All Bio Techne Products
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Quantity:
20 ug
Unit Size:
0.1mg
20µg
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18418531 20 ug 20µg
18705113 - 0.1mg
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Product Code. 18418531 Supplier Novus Biologicals Supplier No. NBP22945520ug

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Description

Mouse Monoclonal Antibody has been used in 6 publications

CD34 Monoclonal specifically detects CD34 in Human, Rat samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD34
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone ICO-115
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Western Blot 0.5-1 ug/mL, Flow Cytometry 0.5 ug/million cells, Immunocytochemistry/Immunofluorescence
Gene Accession No. P28906
Gene Alias CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule
Gene Symbols CD34
Host Species Mouse
Immunogen Blast cells from a chronic myeloid leukemia patient were used as the immunogen for the CD34 antibody.
Purification Method Protein A or G purified
Quantity 20 ug
Regulatory Status RUO
Research Discipline Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 947
Test Specificity This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.
Target Species Human, Rat
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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