CD339 (Jagged 1) Armenian Hamster anti-Mouse, Rat, PE, Clone: HMJ1-29, eBioscience™
Armenian Hamster Monoclonal Antibody
Brand: Affymetrix eBioscience 12-3391-80
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionThis HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen.
The HMJ1-29 antibody is reported to crossreact to rat.
|CD339 (Jagged 1)|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|