CD339 (Jagged 1) Armenian Hamster anti-Mouse, Rat, PE, Clone: HMJ1-29, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-3391-80

25UG ANTI-MOUSE CD339 (JAGGED 1) PE

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15258749

Quantity Price
1 £ 120.0 / 25µg
Estimated Shipment date
from Supplier 20-01-2017
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Description and Specification

Specification

Antigen CD339 (Jagged 1)
Applications Flow Cytometry
Clone HMJ1-29
Concentration 0.2mg/mL
Conjugate PE
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias JAG1, Jagged1
Host Species Armenian Hamster
Isotype IgG
Quantity 25μg
Regulatory Status RUO
Species Reactivity Mouse, Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen.

The HMJ1-29 antibody is reported to crossreact to rat.