CD339 (Jagged 1), PE, clone: HMJ1-29, eBioscience™
Armenian Hamster Monoclonal Antibody
Brand: Affymetrix eBioscience 12-3391-82
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionDescription: This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen.The HMJ1-29 antibody is reported to crossreact to rat.Applications Reported: This HMJ1-29 antibody has been reported for use in flow cytometric analysis.Applications Tested: This HMJ1-29 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|protein jagged-1, JAG1|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
For Research Use Only.