Invitrogen™ CD336 (NKp44) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119302

Product Code. 17780704

Description

CD336 (NKp44) Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.

Specifications

• Antigen: CD336 (NKp44)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NCR2
• Gene Alias: CD336; CD336 antigen; dJ149M18.1; LY95; lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; natural killer cell receptor; NCR2; NK cell activating receptor (NKp44); NK cell-activating receptor; NKP44; NK-p44; NK-p44dJ149M18.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 367216, 9436
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: O95944
• Gene Symbols: NCR2
• Immunogen: Recombinant protein Natural Cytotoxicity Triggering Receptor 2. The antigen corresponds to amino acid range 22-120 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG