CD326 (EpCAM) Rat anti-Mouse, Biotin, Clone: G8.8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-5791-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15229859

Quantity Price
1 £ 117.31 / 100µg
EU Stock 2
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Description and Specification

Specification

Clone G8.8
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Biotin
Antigen CD326 (EpCAM)
Regulatory Status RUO
Applications Flow Cytometry
Quantity 100μg
Isotype IgG2a
Storage Requirements Store at 2-8°C. Do not freeze.
Host Species Rat
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Gene Alias epithelial cell adhesion molecule
Concentration 0.5mg/mL
Format Conjugated

The G8.8 monoclonal antibody reacts with the 40kDa mouse EpCAM (epithelial cellular adhesion molecule), also known as EGP40 (epithelial glycoprotein 40), 17-1A antigen, TACSTD1 (tumor-associated calcium signal transducer 1), and CD326. The immunogen used to generate the G8.8 antibody was the TE-71 thymic epithelial cell line. CD326 is expressed on the majority of epithelial cells, and is considered a pan-carcinoma antigen. CD326 mediates calcium-independent, homophilic, cell-cell adhesion and may function as a growth factor receptor. The antigen is being used as a target for immunotherapy treatment of human carcinomas. CD326 binds LAIR-1 (CD305) and LAIR-2 (CD306) to inhibit cellular activation and inflammation. This epithelial glycoprotein is now recognized as having an important role in tumor biology.