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CD325 (N-Cadherin) Mouse anti-Human, PerCP-eFluor™ 710, Clone: 8C11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-3259-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15599236

  • £238.00 / 100 tests

Estimated Shipment date
from Supplier 03-04-2020

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Description

Description

For a filter configuration, we recommend using the 685 LP dichroic mirror and 710/40 band pass filter, however the 695/40 band pass filter is an acceptable alternative. Our testing indicates that PerCP-eFluor® 710 conjugated antibodies are stable when stained samples are exposed to freshly prepared 2% formaldehyde overnight at 4°C, but please evaluate for alternative fixation protocols. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin′s function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.
Specifications

Specifications

CD325 (N-Cadherin)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P19022
Cadherin-2, Neural-cadherin, CDw325 antigen, CD325, CDHN, NCAD, Cadherin-N
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
8C11
PerCP-eFluor™ 710
CDH2
Liquid
CDH2
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
1000
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