Invitrogen™ CD323 (JAM3) Monoclonal Antibody (CRAM-18 F26)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA528231

Product Code. 16342514

Description

Rat anti Mouse JAM-c antibody, clone CRAM-18 F26 recognizes mouse and human Junctional adhesion molecule C (JAM-C), also known as JAM-3 and, historically, as JAM-2.

JAM3 is involved in tight junctions and represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family.

Specifications

• Antigen: CD323 (JAM3)
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q9D8B7
• Gene Symbols: JAM3
• Immunogen: Recombinant soluble JAM-C.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunocytochemistry
• Clone: CRAM-18 F26
• Conjugate: Unconjugated
• Gene: JAM3
• Gene Alias: 1110002N23Rik; JAM-2; JAM3; JAM-3; JAMC; JAM-C; Jcam3; junction adhesion molecule 3; junction cell adhesion molecule 3; junction cell adhesion molecule C; junctional adhesion molecule 3; Junctional adhesion molecule C; sJAM-C; Soluble form of JAM-C; UNQ859/PRO1868
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 83964
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid