CD32 Mouse anti-Human, PE, Clone: 6C4 (CD32), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-0329-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15546756

Quantity Price
1 £ 84.99 / 25 tests
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Concentration 5μL (0.125μg)/test
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Quantity 25 tests
Species Reactivity Human
Conjugate PE
Format Conjugated
Regulatory Status RUO
Isotype IgG1
Clone 6C4 (CD32)
Host Species Mouse
Antigen CD32

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gamma RII). This antibody recognizes two isoforms of the receptor, Fc gamma RIIA and Fc gamma RIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gamma RII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.