CD32 Mouse anti-Human, FITC, Clone: 6C4 (CD32), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0329-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15556376

Quantity Price
1 £ 47.89 / 25 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 6C4 (CD32)
Primary or Secondary Primary
Isotype IgG1
Applications Flow Cytometry
Host Species Mouse
Regulatory Status RUO
Species Reactivity Human
Concentration 5μL (0.25μg)/test
Format Conjugated
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Antigen CD32
Monoclonal or Polyclonal Monoclonal
Conjugate FITC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25 tests

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.