CD32 Mouse anti-Human, eFluor 450, Clone: 6C4 (CD32), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 48-0329-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15589656

Quantity Price
1 £ 72.77 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Isotype IgG1
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone 6C4 (CD32)
Host Species Mouse
Applications Flow Cytometry
Quantity 25 tests
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test
Antigen CD32
Conjugate eFluor 450
Gene Alias Low Affinity IgG Receptor 2a, FcGR2a, IGFR2
Format Conjugated
Monoclonal or Polyclonal Monoclonal

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay.