missing translation for 'onlineSavingsMsg'
Learn More

CD317 (BST2, PDCA-1), PE, clone: 26F8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-3179-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15546966

  • £168.50 / 100 tests


Estimated Shipment date
from Supplier 03-07-2018
Add to basket

Description

Description

Description: This 26F8 monoclonal antibody reacts with human CD317 (also known as BST2 and tetherin). CD317 is a 30-36-kDa type II transmembrane protein expressed on B cells and bone marrow stromal cells. Although reports have indicated that CD317 mRNA is detectable in activated T cells, protein expression in freshly isolated primary T cells and macrophages is undetectable. Moreover, certain T cell lines, such as Jurkat, do not express detectable levels of CD317 protein. However, CD317 expression can be induced in many cell types (e.g., T and B cells, 293T, and HeLa) by IFNalpha treatment. CD317 has been associated with pre-B cell growth and the terminal differentiation of plasma B cells. More recently, this molecule has been reported to prevent HIV-1 virion release from the surface of infected cells, leading to reuptake and degradation of the virus. This activity is inhibited by the HIV-1 accessory protein Vpu. CD317 has been identified as the ligand for the ILT7 receptor.Applications Reported: This 26F8 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 26F8 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD317
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q10589
Bone marrow stromal cell antigen 2, Tetherin, PDCA-1, 2310015I10Rik, Bst-2, C87040, DAMP-1, GREG, DAMP-1 protein homolog, HM1.24 antigen, bone marrow stromal antigen 2
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
26F8
PE
BST2
Conjugated
BST2
IgG1, kappa
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
684
Videos

For Research Use Only.