CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio927), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-3172-025

Product Code. 17121212

Description

The eBio927 MAb reacts with PDCA-1 (BST2, CD317), a specific marker of plasmacytoid dendritic cells (pDC), also known as type I IFN-producing cells (IPC) in the naive mouse. Mouse IPCs are typically CD11c+, CD11b-, B220+, Ly-6C+, and CD62L+. PDCA-1 is predominantly expressed by IPCs in the naive mouse which represents a very minor population (<0.5%) of splenocytes. It is upregulated on numerous cell types following stimulation which triggers an IFN response. PDCA-1 cycles between cell surface and intracellular compartments and may function to regulate trafficking of secreted cytokines. PDCA-1 (BST2) is the protein recognized by antibody 120G8. The eBio927 MAb has also been shown to have functional activity. The epitope recognized by eBio927 is distinct from eBio129c; thus, the antibodies can be used to costain, purify and identify pDCs.

CD317 (BST2, PDCA-1) Monoclonal antibody specifically detects CD317 (BST2, PDCA-1) in Mouse samples. It is validated for Flow Cytometry, Functional Assay

Specifications

• Antigen: CD317 (BST2, PDCA-1)
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: Q8R2Q8
• Host Species: Rat
• Quantity: 25 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Flow Cytometry, Functional Assay
• Clone: eBio927
• Conjugate: Functional Grade
• Gene: Bst2
• Gene Alias: 2310015I10Rik; Bone marrow stromal antigen 2; bone marrow stromal cell antigen 2; Bst2; BST-2; C87040; CD317; Damp1; DAMP-1; DAMP-1 protein homolog; GREG; HM1.24 antigen; NPC-A-7; PDCA-1; protein DAMP-1; TETHERIN
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 69550
• Content And Storage: 4° C
• Form: Liquid

For Research Use Only.