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CD301b (MGL2) Monoclonal Antibody (11A10-B7), eFluor™ 660, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£90.00 - £250.00
Specifications
Antigen | CD301b (MGL2) |
---|---|
Clone | 11A10-B7 |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15559926
|
Affymetrix eBioscience
50-3011-82 |
100 μg |
£250.00
100µg |
Estimated Shipment: 05-06-2024 Log in to see stock. |
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15549926
|
Affymetrix eBioscience
50-3011-80 |
25 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The monoclonal antibody 11A10-B7 recognizes mouse CD301b. CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming. Applications Reported: This 11A10-B7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 11A10-B7 antibody has been tested by flow cytometric analysis of mouse skin draining lymph node cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor™ 660 is a replacement for Alexa Fluor™ 647. eFluor™ 660 emits at 659 nm and is excited with the red laser (633 nm).
CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.Specifications
CD301b (MGL2) | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
216864 | |
IgG2a λ | |
Affinity chromatography | |
Antibody |
11A10-B7 | |
Flow Cytometry | |
eFluor 660 | |
Rat | |
Mouse | |
Mgl2 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Mgl2 |
For Research Use Only.