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CD301b (MGL2) Monoclonal Antibody (11A10-B7), eFluor™ 660, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£90.00 - £269.00
Specifications
| Antigen | CD301b (MGL2) |
|---|---|
| Clone | 11A10-B7 |
| Concentration | 0.2 mg/mL |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
Description
Description: The monoclonal antibody 11A10-B7 recognizes mouse CD301b. CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming. Applications Reported: This 11A10-B7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 11A10-B7 antibody has been tested by flow cytometric analysis of mouse skin draining lymph node cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor™ 660 is a replacement for Alexa Fluor™ 647. eFluor™ 660 emits at 659 nm and is excited with the red laser (633 nm).
CD301b is also known as macrophage galactose-type C-type lectin 2 (MGL2). CD301b expression is restricted to dermal dendritic cells, connection tissue, and bone marrow derived dendritic cells. Macrophages also express CD301b at low levels. CD301b contains a single carbohydrate recognition domain that recognizes protein antigens that have a galactose and N-acetylgalactosamine (Gal/GalNAc). Gal/GalNAc protein antigens are efficiently internalized through CD301b and presented to antigen specific CD4+ cells via MHC Class II. CD301b+ dendritic cells are believed to play an important role in TH2 priming.Specifications
| CD301b (MGL2) | |
| 0.2 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| 216864 | |
| IgG2a λ | |
| Affinity chromatography | |
| Antibody |
| 11A10-B7 | |
| Flow Cytometry | |
| eFluor 660 | |
| Rat | |
| Mouse | |
| Mgl2 | |
| Primary | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Mgl2 |
For Research Use Only.
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