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Invitrogen™ CD2AP Polyclonal Antibody
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Product Code. 15779830 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15779830 100 μL 100µL
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Product Code. 15779830 Supplier Invitrogen™ Supplier No. PA551879

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WSGTLNNKLG LFPSNFVKEL EVTDDGETHE AQDDSETVLA GPTSPIPSLG NVSETASGSV TQPKKIRGIG FGDIFKEGSV KLRTRTSSSE TEEKKPEKPL ILQSLGPKTQ SVEITKTDTE GKIKAKE Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 83%.

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD2AP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CD2AP
Gene Accession No. F1LRS8, Q9JLQ0, Q9Y5K6
Gene Alias adapter protein CMS; AL024079; C78928; Cas ligand with multiple SH3 domains; Cas ligand with multiple Src homology 3 (SH3) domains; CD2 associated protein; Cd2ap; CD2-associated protein; CMS; mesenchyme to epithelium transition protein, SH3 domains; mesenchyme-to-epithelium transition protein with SH3 domains 1; Mets1; METS-1; SH3 domain-containing adapter protein; SH3 domain-containing adaptor protein METS-1
Gene Symbols CD2AP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CD2AP. Recombinant protein control fragment (Product #RP-101069).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12488, 23607, 316258
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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