CD298 Mouse, anti-Human, APC, Clone: LNH-94, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60159AZ

Product Code. 17149211

Description

• The LNH-94 antibody reacts with human CD298, the β3 subunit of the Na+/K+ ATPase
• The Na+/K+ ATPase is a 42 kDa type II transmembrane protein composed of four catalytic α subunits and three smaller glycosylated non-catalytic β subunits
• The Na+/K+ ATPase is important for establishing electrochemical gradients and maintaining normal resting membrane potential by coupling ATP hydrolysis to the active transport of Na+ and K+
• The β subunits have been reported to act as chaperones that stabilize the α subunits and occlude K+
• CD298 has been used to identify metastatic human cancer cells in mouse xenograft models and has been reported to modulate aspects of immunity, including HIV production, and T cell and B cell activation
• CD298 is found on leukocytes, platelets, and most other tissue types

Specifications

• Antigen: CD298
• Classification: Monoclonal
• Conjugate: APC
• Quantity: 100 Tests
• Target Species: Human
• Cell Type: B Cells, Granulocytes and Subsets, Lymphocytes, Mammary Cells, Monocytes, T Cells

• Applications: Flow Cytometry
• Clone: LNH-94
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG1 κ