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CD29 Rat anti-Mouse, Clone: KMI6, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0292-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15206897

  • £140.02 / 500µg


Estimated Shipment
31-10-2017
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Disclaimers:

For Research Use Only.


Description

Description

The KMI6 monoclonal antibody reacts with mouse CD29 (integrin β1), a 120-130kDa member of the β integrin family expressed by leukocytes, endothelial, smooth muscle and epithelial cells. CD29 binds non-covalently with the α integrins CD49a-f, to form the VLA-1 through VLA-6 complexes, respectively, and also with CD51. These αβ integrin heterodimers are capable of mediating a variety of cellular responses including adhesion, trafficking, proliferaton and differentiation. All of the integrins which include CD29 bind to extracellular matrix proteins including collagen, laminin, fibronectin and vitronectin, whereas some CD29-containing integrins also interact with cellular receptors including VCAM-1 and MadCAM-1. The KMI6 antibody has been shown to be an activating antibody for β1 integrins, enhancing lymphocyte binding to fibronectin.
Specifications

Specifications

CD29
KMI6
Unlabeled
Purified
Rat
500μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Integrin Beta 1, ITGB1, Fibronectin Receptor Beta, VLA-Beta
IgG2a
RUO
Primary
Murine