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CD283 (TLR3) Mouse anti-Human, PE, Clone: TLR3.7, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9039-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15229349

  • £109.45 / 25µg


Estimated Shipment date
from Supplier 25-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The TLR3.7 monoclonal antibody reacts with human Toll-like receptor 3 (TLR3). To date, at least twelve members of the Toll-like receptor family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. In the innate immune response, TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial activity. TLR3 recognizes double-stranded (ds)RNA, induces the activation of NF-κB through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). TLR3.7 suppressed poly(I):poly(C)-mediated IFN-β production by human fibroblasts naturally expressing TLR3 on their surface.
Description & Specifications

Specifications

CD283 (TLR3)
TLR3.7
PE
Conjugated
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TLR-3, toll-like receptor 3
IgG1
RUO
Primary
Human