CD282 (TLR2) Rat anti-Mouse, FITC, Clone: 6C2, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-9021-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15228379

Quantity Price
1 £ 72.77 / 25µg
EU Stock 5
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Description and Specification

Specification

Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen CD282 (TLR2)
Species Reactivity Mouse
Quantity 25μg
Clone 6C2
Isotype IgG2b
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Host Species Rat
Regulatory Status RUO
Conjugate FITC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias TLR-2, toll-like receptor 2
Applications Flow Cytometry
Concentration 0.5mg/mL

The 6C2 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.