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CD279 (PD-1) Mouse anti-Human, PerCP-eFluor 710, Clone: MIH4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-9969-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15549476

  • £87.96 / 25 tests


Estimated Shipment date
from Supplier 29-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The MIH4 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55kDa member of the immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. The MIH4 antibody recognizes a different epitope than antibody clones J105.
Description & Specifications

Specifications

CD279 (PD-1)
MIH4
PerCP-eFluor 710
Conjugated
IgG1
RUO
Primary
Human
Flow Cytometry
5μL (1.0μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal