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  6. CD273 (B7-DC) Monoclonal Antibody (TY25), Functional Grade, eBioscience™, Invitrogen™

CD273 (B7-DC) Monoclonal Antibody (TY25), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£2595.00 - £12950.00

Specifications

Antigen CD273 (B7-DC)
Clone TY25
Concentration 1 mg/mL
Applications Flow Cytometry, Functional Assay, Neutralization
Classification Monoclonal
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Affymetrix eBioscience
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Description

Description

The TY25 MAb reacts with mouse B7-DC/PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of ∽25 kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by sub-populations of dendritic cells, monocytes and macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, but binds PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. TY25 is a useful tool to study the exact function of B7-DC/PD-L2 in APC/T cell interaction and to characterize the expression pattern of this molecule in mouse.

CD273 (B7-DC) Monoclonal antibody specifically detects CD273 (B7-DC) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Neutralization
Specifications

Specifications

CD273 (B7-DC)
1 mg/mL
Monoclonal
Liquid
RUO
PBS with no preservative; pH 7.2
B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; F730015O22Rik; MGC124039; MGC124040; PD1 ligand 2; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; PDCD1LG2; Pdl2; PD-L2; Programmed cell death 1 ligand 2; programmed death ligand 2
IgG2a κ
Affinity chromatography
Antibody
TY25
Flow Cytometry, Functional Assay, Neutralization
Functional Grade
Rat
Mouse
Q9WUL5
58205
Primary
4° C
PDCD1LG2
Videos
SDS
Documents

Documents

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