CD27 Armenian Hamster anti-Human, Mouse, Clone: LG.3A10, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0272-81

50UG:ANTI-HUMAN/MOUSE CD27 FUNCTIONAL GRADE

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15278407

Quantity Price
1 £ 88.0 / 50µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Antigen CD27
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Clone LG.3A10
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias TNFRSF7
Host Species Armenian Hamster
Isotype IgG
Quantity 50μg
Regulatory Status RUO
Species Reactivity Human, Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The LG.3A10 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8- precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.8F10 cross-reacts with human and rat CD27.
When the monoclonal antibody LG.3A10 is crosslinked on purified T cells, proliferation is increased. In the absence of crosslinking, the antibody inhibits CD27-CD70 interaction.