CD268 (BAFF Receptor) Monoclonal Antibody (8A7), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-9117-025

Product Code. 17171572

Description

The 8A7 monoclonal antibody reacts with the human BAFF receptor, also known as B lymphocyte stimulator (BLyS protein) receptor, which is expressed on B cells. The ligand for this receptor, BAFF (B cell-activating factor of the TNF family) is a B cell survival factor and regulates CD21/35 and CD23 expression. Interaction of this ligand with its receptor causes elevated CD21/35 and CD23 expression, whereas receptor blockade has been shown to down-modulate expression. Applications Reported: The 8A7 antibody has been reported for use in flow cytometric analysis. It has also been reported for use in functional assays. Applications Tested: The 8A7 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/ μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.

CD268 (BAFF Receptor) Monoclonal antibody specifically detects CD268 (BAFF Receptor) in Human samples. It is validated for Flow Cytometry, Functional Assay

Specifications

• Antigen: CD268 (BAFF Receptor)
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: Q96RJ3
• Host Species: Mouse
• Quantity: 25 mg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Functional Assay
• Clone: 8A7
• Conjugate: Functional Grade
• Gene: TNFRSF13C
• Gene Alias: 2010006P15Rik; B cell-activating factor receptor; BAFF receptor; BAFFR; BAFF-R; B-cell maturation defect; B-cell maturation defect 1; B-cell-activating factor receptor; Bcmd; Bcmd1; Bcmd-1; BLyS receptor 3; BR3; BROMIX; CD268; CVID4; Lvis22; prolixin; RGD1560810; TNF receptor superfamily member 13C; Tnfrsf13c; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13c
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115650
• Content And Storage: 4° C
• Form: Liquid