Invitrogen™ CD267 (TACI) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110998

Product Code. 17128923

Description

Immunogen sequence: ACFLKKRGDP CSCQPRSRPR QSPAKSSQDH AMEAGSPVST SPEPVETCSF CFPECRAPTQ ESAVTPGTPD PTCAGRWGCH TRTTVLQPCP HIPDSGLGIV CVPAQE Highest antigen sequence indentity to the following orthologs: Rat - 40%, Mouse - 43%.

Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

Specifications

• Antigen: CD267 (TACI)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TNFRSF13B
• Gene Alias: 1200009E08Rik; CD267; CVID; CVID2; IGAD2; NEWGENE_1595998; RYZN; TACI; TNF receptor superfamily member 13B; Tnfrsf13b; TNFRSF14B; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23495
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14836
• Gene Symbols: TNFRSF13B
• Immunogen: Recombinant Protein corresonding to Human CD267 (TACI). Recombinant protein control fragment (Product #RP-102143).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG