CD267 (TACI) Mouse anti-Human, Clone: 11H3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9217-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15278157

Quantity Price
1 £ 60.53 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Format Purified
Applications Flow Cytometry
Applications Functional Assay
Antigen CD267 (TACI)
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Clone 11H3
Host Species Mouse
Species Reactivity Human
Concentration 0.5mg/mL
Isotype IgG2a
Regulatory Status RUO
Conjugate Unlabeled
Gene Alias TNFRSF13B
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.

The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI.