CD235ab (Glycophorin A/B) Mouse, anti-Human, Unconjugated, Clone: HIR2 (GA-R2), STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60111

Product Code. 17119101

Description

• The HIR2 (GA-R2) antibody recognizes an epitope common to the N-terminal region of human CD235a (glycophorin A) and CD235b (glycophorin B), homologous type I sialoglycoproteins of the erythrocyte (red blood cell) membrane that bear the antigenic determinants for the MN and Ss blood groups
• CD235ab is expressed on early- and late-stage erythroblasts, mature erythrocytes, and erythroid cell lines such as K562 and HEL, but not on other cell types
• CD235a is abundantly expressed whereas CD235b is a relatively minor membrane component
• The proteins are believed to provide a large mucin-like surface to erythrocytes that acts to minimize aggregation in the circulation
• The HIR2 antibody binds with higher affinity to CD235a than CD235b, and agglutinates untreated erythrocytes

Specifications

• Antigen: CD235ab (Glycophorin A/B)
• Classification: Monoclonal
• Conjugate: Unconjugated
• Quantity: 100 μg
• Target Species: Human
• Cell Type: Red Blood Cells

• Applications: Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: HIR2 (GA-R2)
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG2b κ