CD223 (Lag-3) Mouse anti-Human, PE-Cy7, Clone: 3DS223H, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-2239-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15518526

Quantity Price
1 £ 86.73 / 25 tests
EU Stock 7
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Description and Specification

Specification

Concentration 5μL (0.06μg)/test
Primary or Secondary Primary
Applications Flow Cytometry
Isotype IgG1
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Clone 3DS223H
Species Reactivity Human
Conjugate PE-Cy7
Gene Alias Lymphocyte Activation Gene-3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Quantity 25 tests
Monoclonal or Polyclonal Monoclonal
Antigen CD223 (Lag-3)
Host Species Mouse

This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

This 3DS223H antibody will recognize a formaldehyde-fixed epitope.