CD209a (DC-SIGN) Mouse anti-Mouse, Alexa Fluor 488, Clone: MMD3, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 53-2094-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionThis MMD3 monoclonal antibody recognizes mouse CD209a, which is also known as DC-SIGN. CD209a is a type II transmembrane C-type lectin expressed on a subset of dendritic cells, including some CD4+, CD8- and plasmacytoid pre-dendritic cells. Studies indicate that CD209a expression can vary according to the activation state of the host. Moreover, CD209a is down-regulated in spleen-derived dendritic cell cultures supplemented with GM-CSF. CD209a is involved in mediating the innate immune response by binding microbial carbohydrates.
Cross-blocking studies suggest that MMD3 recognizes a different a different epitope from LWC06 and 5H10.
|Alexa Fluor 488|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|