Invitrogen™ CD205 Monoclonal Antibody (IL-A114), PE

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA528316

Product Code. 16382584

Description

Mouse anti Bovine CD205 antibody, clone IL-A114 recognizes bovine CD205 (also known as DEC205) and originally described as BoWC6. Reconstitute by adding 1 mL distilled water.

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.

Specifications

• Antigen: CD205
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
• Gene Accession No.: 0
• Gene Symbols: LY75
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 407236
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Lyophilized

• Applications: Flow Cytometry
• Clone: IL-A114
• Conjugate: PE
• Gene: LY75
• Gene Alias: CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4
• Host Species: Mouse
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Bovine
• Product Type: Antibody
• Isotype: IgG1