CD201 (EPCR) Monoclonal Antibody (eBio1560 (1560)), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-2012-050

Product Code. 17101192

Description

The eBio1560 MAb reacts with mouse Endothelial Protein C Receptor (EPCR, CD201), a 25 kDa Type 1 transmembrane protein expressed on endothelial cells. EPCR exhibits sequence and structural homology with the MHC class I/CD1 family of proteins. EPCR is a ligand for Protein C and plays an important role in augmenting Protein C activation by the thrombin-thrombomodulin complex and in regulating blood coagulation and inflammation. Deletion of EPCR results in embryonic lethality, at least partically due to placental thrombosis. Recently, it was demonstrated that EPCR expression identified cells in the bone marrow that are capable of hematopoietic reconstitution activity comparable to hematopoietic stem cells isolated with conventional methods. The eBio1560 MAb can be used for the detection of these hematopoietic stem cells, however the eBiomRCR-16 MAb should only be used for the detection of CD201 on endothelial cells.

CD201 (EPCR) Monoclonal antibody specifically detects CD201 (EPCR) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunohistochemistry, Neutralization

Specifications

• Antigen: CD201 (EPCR)
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: Q64695
• Host Species: Rat
• Quantity: 50 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry, Neutralization
• Clone: eBio1560 (1560)
• Conjugate: Functional Grade
• Gene: Procr
• Gene Alias: activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; Centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19124
• Content And Storage: 4° C
• Form: Liquid