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CD200 Monoclonal Antibody (OX90), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 46-5200-82
Code : Z2
Additional Details : Weight : 0.25000kg
Description
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants.
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.Specifications
CD200 | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
O54901 | |
Cd200 | |
Affinity chromatography | |
RUO | |
17470 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
OX90 | |
PerCP-eFluor 710 | |
Cd200 | |
antigen identified by monoclonal antibody MRC OX-2; CD200; Cd200 antigen; Cd200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-OX2); Cspmo2; hypothetical protein LOC534910; MOX1; MOX2; MRC; MRC OX-2 antigen; MRCOX2; My033; OX2; OX-2; OX-2 membrane glycoprotein | |
Rat | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG2a κ |
For Research Use Only.