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CD19 Antibody (CVID3/429), PE, Novus Biologicals™

Product Code. 18249504 Shop All Bio Techne Products
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Product Code. 18249504 Supplier Novus Biologicals Supplier No. NBP261909PE

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Mouse Monoclonal Antibody

CD19 Monoclonal specifically detects CD19 in Human, Monkey, Chimpanzee samples. It is validated for Flow Cytometry, Product Image.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD19
Applications Flow Cytometry
Classification Monoclonal
Clone CVID3/429
Conjugate PE
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Gene Symbols CD19
Host Species Mouse
Immunogen Recombinant full-length human CD19 protein (Uniprot: P15391)
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, B Cell Development and Differentiation Markers, Cytokine Research, Immunology, Mesenchymal Stem Cell Markers, Myeloid derived Suppressor Cell, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 930
Test Specificity CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms
Target Species Human, Monkey, Primate
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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