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CD184 (CXCR4) Rat anti-Mouse, eFluor® 450, Clone: 2B11, eBioscience™

Rat Monoclonal Antibody

£86.25 - £200.00

Specifications

Antigen CD184 (CXCR4)
Clone 2B11
Target Species Mouse
Conjugate eFluor™ 450
Isotype IgG2b, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15569856 View Documents Affymetrix eBioscience
48-9991-80
25 μg £86.25
25µg View alternative products
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Estimated Shipment date
from Supplier 16-04-2020
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15579856 View Documents Affymetrix eBioscience
48-9991-82
100 μg £200.00
100µg View alternative products
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»
EU Stock 1 Please to purchase this item. Need a web account? Register with us today!
Description

Description

eFluor™ 450 is an alternative to Pacific Blue™. eFluor™ 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.2 μm post-manufacturing filtered. Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
Specifications

Specifications

CD184 (CXCR4)
Mouse
IgG2b, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
2B11
eFluor™ 450
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.