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Invitrogen™ CD177 Polyclonal Antibody

Description
Immunogen sequence: CQFGTVQHVW KVSDLPRQWT PKNTSCDSGL GCQDTLMLIE SGPQVSLVLS KGCTEAKDQE PRVTEHRMGP GLSLISYTFV CRQEDFCNNL VNSLP Highest antigen sequence indentity to the following orthologs: Mouse - 62%, Rat - 56%.
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
Specifications
Specifications
| Antigen | CD177 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CD177 |
| Gene Accession No. | Q8N6Q3 |
| Gene Alias | 1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181 |
| Gene Symbols | CD177 |
| Show More |
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