missing translation for 'onlineSavingsMsg'
Learn More

CD16 Mouse anti-Human, PE, Clone: B73.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0167-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15576716

  • £165.00 / 100 tests

EU Stock 3

Please to purchase this item. Need a web account? Register with us today!


Description

Description

CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.
Specifications

Specifications

CD16
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P08637, O75015
FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
B73.1
PE
FCGR3A
Liquid
FCGR3A, FCGR3B
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
2214, 2215
Videos
Documents

For Research Use Only.