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CD16/CD32 Rat, anti-Mouse, Unconjugated, Clone: 2.4G2, STEMCELL Technologies
Rat Monoclonal Antibody
£183.60 - £583.20
Specifications
| Antigen | CD16/CD32 |
|---|---|
| Clone | 2.4G2 |
| Applications | Immunoprecipitation, Flow Cytometry, Immunofluorescence, Functional Assay |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17119221
|
Stemcell Technologies
60161.2 |
100 μg |
£183.60
100µg |
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|
17109221
|
Stemcell Technologies
60161.1 |
500 μg |
£363.15
500µg |
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|
17199211
|
Stemcell Technologies
60161 |
1 mg |
£583.20
1mg |
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Description
- The 2.4G2 antibody reacts with a shared epitope of Fc-gamma receptors CD16 (FcRIII) and CD32 (FcRII) in the mouse
- CD16 and CD32 are low affinity receptors for the Fc portion of IgG, with CD32 having a higher affinity for IgG aggregates and immune complexes
- CD16 and CD32 are expressed on B cells, monocytes, macrophages, NK cells, neutrophils, granulocytes, mast cells, and dendritic cells
- The binding of immunoglobulins to Fc receptors is involved in multiple immunological functions, including phagocytosis, cytotoxocity, and the modulation of immune responses
- The 2.4G2 antibody blocks the interaction between IgG and CD16 or CD32, and therefore is used as a pre-treatment to minimize non-specific binding of antibodies to FcR-bearing cells in applications such as flow cytometry, cell sorting, and immunofluorescence
Specifications
| CD16/CD32 | |
| Immunoprecipitation, Flow Cytometry, Immunofluorescence, Functional Assay | |
| Unconjugated | |
| Mouse | |
| Primary |
| 2.4G2 | |
| Monoclonal | |
| Rat | |
| IgG2b κ |
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