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CD158f Mouse anti-Human, PE, Clone: UP-R1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1588-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15586906

  • £195.05 / 100 tests


Estimated Shipment date
from Supplier 04-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR (Killer cell Ig-like receptors) family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain.

The UP-R1 antibody has been shown to inhibit NK cytotoxicity.
Description & Specifications

Specifications

CD158f
UP-R1
PE
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
Conjugated
KIR2DL5/S5, KIR
IgG1
RUO
Primary
Human