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Invitrogen™ CD156A/EGFR Biosimilar Recombinant Human Monoclonal Antibody
Human Recombinant Monoclonal Antibody
£483.00 - £2005.00
Specifications
| Antigen | CD156A/EGFR Biosimilar |
|---|---|
| Concentration | 1 mg/mL |
| Content And Storage | -20°C, Avoid Freeze/Thaw Cycles |
| Applications | ELISA, Flow Cytometry, Functional Assay |
| Classification | Recombinant Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30283132
|
Invitrogen™
MA560143 |
100 μg |
£483.00
100µg |
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|
30284380
|
Invitrogen™
MA560144 |
1 mg |
£2005.00
1mg |
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Description
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
The CD156A gene, also known as ADAM8 (a disintegrin and metalloprotease 8), is a cell surface antigen highly expressed in monocytic lineages, with a significant role in neurodegenerative diseases and cancer. It is a membrane-anchored metalloprotease with a long extracellular region containing domains similar to hemorrhagic snake venom proteins. ADAM8 is involved in the regulation of cell adhesion and proteolysis. The gene encoding CD156A is located on human chromosome 10q26.3. Meanwhile, the EGFR gene, or epidermal growth factor receptor, is part of the ErbB family of receptor tyrosine kinases located on chromosome 7p11.2. EGFR plays a crucial role in regulating cell proliferation, differentiation, survival, and migration. It is a 170-kDa transmembrane glycoprotein and is heavily implicated in various cancers, including non-small-cell lung cancer and glioblastoma due to mutations or overexpressions. Both genes are critical for cell communication and regulation processes, with significant implications for cancer therapy and neurodegenerative disease research.Specifications
| CD156A/EGFR Biosimilar | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Recombinant Monoclonal | |
| Lyophilized | |
| IgG1 | |
| Human | |
| Primary | |
| Protein A |
| 1 mg/mL | |
| ELISA, Flow Cytometry, Functional Assay | |
| Unconjugated | |
| Human | |
| RUO | |
| 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Antibody |
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