CD154 (CD40 Ligand) Mouse anti-Human, Clone: 24-31, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1548-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15267257

Quantity Price
1 £ 54.42 / 25µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Host Species Mouse
Species Reactivity Cynomolgus, Human
Clone 24-31
Regulatory Status RUO
Conjugate Unlabeled
Gene Alias CD40L
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Isotype IgG1
Format Purified
Applications Flow Cytometry
Applications Functional Assay
Storage Requirements Store at 2-8°C.
Antigen CD154 (CD40 Ligand)

The 24-31 monoclonal antibody reacts with human CD154, a 39kDa transmembrane glycoprotein also known as gp39 and CD40 ligand (CD40L). CD154 is a member of the TNF superfamily and is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells including B cells, monocytes/macrophages and dendritic cells, CD154 serves a crucial function in T-APC cognate interaction. CD154 interaction with CD40 transduces signals for T-dependent B-cell activation and induces B cell cycle entry. 24-31 cross-reacts with the cynomolgus monkey CD154.