CD150 Rat anti-Mouse, PE, Clone: mShad150, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-1502-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15208689

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Description and Specification

Specification

Quantity 25μg
Primary or Secondary Primary
Gene Alias SLAM, Signaling lymphocyte activation molecule
Host Species Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone mShad150
Conjugate PE
Concentration 0.2mg/mL
Species Reactivity Mouse
Applications Flow Cytometry
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD150
Isotype IgG2b

The mShad150 monoclonal antibody reacts with mouse CD150, an ∽70kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T cells, in particular Th1, and B cells; this expression is rapidly upregulated upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM in T cells induces proliferation and augmentation of the interferon-gamma response. Furthermore, SLAM is thought to play a role in adhesion between the T cell and antigen-presenting cell. The mShad150 antibody has been reported to also stain the CD150+CD244-CD48-CD41- population of pluripotent hematopoietic stem cells.