CD150 Rat anti-Mouse, APC, Clone: 9D1, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-1501-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15390680

Quantity Price
1 £ 115.56 / 50µg
EU Stock 6
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Description and Specification

Specification

Conjugate Allophycocyanin
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Quantity 50μg
Primary or Secondary Primary
Antigen CD150
Applications Flow Cytometry
Isotype IgG1
Regulatory Status RUO
Clone 9D1
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias SLAM, IPO-3, IPO3, SLAMF1
Concentration 0.2mg/mL
Host Species Rat
Format Conjugated

The 9D1 monoclonal antibody reacts with mouse CD150, an ∽70kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T (especially TH1) and B cells and its expression is rapidly upregulated on these cells upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM in T cells induces proliferation and augmentation of the interferon-gamma response. Furthermore, SLAM is thought to play a role in adhesion between the T cell and antigen-presenting cell. 9D1 is reported to be an activating antibody.

Mouse hematopoietic stem cells (HSC) can be identified using SLAM family markers, such as CD150+CD244-CD48-. For this application we recommend the use of antibody clone mShad150 (cat. 12-1502).